entrepreneurial resources
Additional entrepreneurial resources and funding opportunities in the Great Plains Hub play a crucial role in fostering entrepreneurship and facilitating innovative projects. These avenues provide essential financial resources for entrepreneurs and researchers to advance their work in technology commercialization or business development. By empowering individuals to develop prototypes, engage with customers, and scale their ventures, these funding opportunities contribute to economic growth, talent attraction, and the cultivation of a dynamic entrepreneurial ecosystem within the region.

federal opportunities
The U.S. National Science Foundation Innovation Corps (I-Corps™) program is an immersive, entrepreneurial training program that facilitates the transformation of invention to impact.
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The Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs, America’s Seed Fund awards provide equity free funding through federal agencies to American small businesses.
north dakota
The ND SBDC network of credentialed business advisors empower North Dakota small businesses and entrepreneurs to thrive. We accelerate business growth in communities across North Dakota by providing customized guidance and resources that help owners and entrepreneurs achieve their goals at every stage of their business life cycle.
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South dakota
Designed to assist South Dakota entrepreneurs and small businesses with beginning and expanding their business through the Governor’s Giant Vision Competition and SBIR/STTR funding.
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The South Dakota Small Business Development Center (SBDC) helps new entrepreneurs realize their dream of business ownership and assists existing businesses in their efforts to remain competitive.
An ecosystem organization that empowers founders by offering resources to network, launch, and grow their ventures.
South Dakota’s low cost of doing business and aggressive financing programs can have a substantial effect on your bottom line. When combined with incentives from the community, region and other sources, a Rapid City location makes good bottom-line sense.
Montana
The Rocky Mountain Research Evaluation And Commercialization Hub (RMT-REACH) is seeking proposals for their 2025 RMT-REACH Pilot Cohort to support the translational advancement of promising health innovations in academic institutions across Montana, Alaska, Idaho, and Wyoming. The program supports proof-of-concept and go-to-market strategy activities through milestone-driven funding. Supported innovations may span the spectrum of health outcomes, including therapeutics, preventatives, diagnostics, devices, methods, or research tools that move the needle forward on unmet patient and public health needs.
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Free one-on-one business consulting. The SBDC can help with a large variety of business issues, ranging from basic start-up issues, to assisting with finance issues, preparing business plans and marketing assistance.
Expert Business Advisors that assist business owners and aspiring entrepreneurs for no cost, one-on-one advising and low-cost training, customized to meet your needs.
wyoming
The Rocky Mountain Research Evaluation And Commercialization Hub (RMT-REACH) is seeking proposals for their 2025 RMT-REACH Pilot Cohort to support the translational advancement of promising health innovations in academic institutions across Montana, Alaska, Idaho, and Wyoming. The program supports proof-of-concept and go-to-market strategy activities through milestone-driven funding. Supported innovations may span the spectrum of health outcomes, including therapeutics, preventatives, diagnostics, devices, methods, or research tools that move the needle forward on unmet patient and public health needs.
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The Wyoming SBDC Network is a partnership between the University of Wyoming, the Wyoming Business Council, and the U.S. Small Business Administration offering business expertise and technical assistance to help you start, grow, reinvent, or exit your business.
IMPACT 307 provides innovation-driven business incubators in Laramie and Casper, Wyoming.
NEBRASKA
The Nebraska Small Business Development Center (SBDC) program is a resource for small business creation and expansion in Nebraska. The Nebraska SBDC offers confidential consulting services to entrepreneurs and small business owners looking to start and grow their enterprises or to transition companies to the next generation of ownership.
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KANSAS
The Kansas Small Business Development Center network is a statewide, inter-institutional program to enhance economic growth in Kansas by providing management, marketing, and technical assistance to small businesses.
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The Impact Investment Center is your gateway to starting and growing a business in Kansas. We connect entrepreneurs with a network of over 650+ resource partners across the state, providing the expertise, education, and financial resources
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Funded by North Dakota State University’s Research and Creative Activity office, this is an opportunity designed to empower innovators with up to $10,000 in funding towards building a minimum viable product.
Aid for Technical Leads looking to advance their projects through sustained customer engagement and feedback, ensuring that their innovations are continually aligned with market demands and opportunities. Funded by North Dakota State University’s Research and Creative Activity office.